SLUG antibody
Quick Overview for SLUG antibody (ABIN4952602)
Target
See all SLUG (SNAI2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antigen affinity
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Immunogen
- Amino acids KLSDPHAIEAEKFQCNLCNKTYSTFSGLAKHKQ of human SLUG were used as the immunogen for the SLUG antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the SLUG antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- After reconstitution, the SLUG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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Alternative Name
- SLUG / SNAI2
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Background
- SLUG is also known as SNAI2. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
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UniProt
- O43623
Target
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